Heart disease is a major cause of death and disability worldwide, with chronic heart failure being a common condition associated with significant morbidity and mortality. Depression is also prevalent in people with heart failure, which can further worsen their overall health outcomes. This has led to the search for alternative treatments that can improve both physical and mental health in patients with heart disease. Are there solutions? Are mushrooms on the precipice of research for aiding heart conditions?
One potential treatment that has gained attention in recent years is the use of magic mushrooms, which have been used for centuries for their mind-healing properties. However, it is unclear whether they are safe for people with heart conditions. A recent study aimed to investigate the potential effects and safety of magic mushrooms in heart disease conditions.
The study examined the effects of two types of magic mushrooms – Panaeolus cyanescens and Psilocybe cubensis – on cells in the heart. These mushrooms contain a psychoactive compound called psilocybin, which is known to have a profound effect on perception, mood, and consciousness. The researchers wanted to determine whether the mushrooms could help improve heart health and protect against cell damage.
To conduct the study, the mushrooms were oven-dried and extracted using both cold and boiling-hot water. H9C2 cardiomyocytes, which are heart muscle cells, were induced with endothelin-1, a peptide that contributes to heart hypertrophy, prior to treatment with extracts over 48 hours. Cell injury was stimulated with tumor necrosis factor-α (TNF- α). The results showed that the water extracts of Panaeolus cyanescens and Psilocybe cubensis did not aggravate the pathological hypertrophy induced by endothelin-1 and also protected against the TNF-α-induced injury and cell death in concentrations used.